Cargando…

The Clinical Trials Mosaic: Toward a Range of Clinical Trials Designs to Optimize Evidence-Based Treatment

OBJECTIVE: Dichotomizing clinical trials designs into nomothetic (e.g., randomized clinical trials or RCTs) versus idiographic (e.g., N-of-1 or case studies) precludes use of an array of hybrid designs and potential research questions between these extremes. This paper describes unique clinical evid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ridenour, Ty A., Chen, Szu-Han K., Liu, Hsin-Yi, Bobashev, Georgiy V., Hill, Katherine, Cooper, Rory
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Scandinavian Society for Person-Oriented Research 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842613/ https://www.ncbi.nlm.nih.gov/pubmed/33569122 http://dx.doi.org/10.17505/jpor.2017.03

Ejemplares similares

myEpi. Epidemiology of One
por: Bobashev, Georgiy
Publicado: (2014)

Power analysis for idiographic (within-subject) clinical trials: Implications for treatments of rare conditions and precision medicine
por: Tueller, Stephen, et al.
Publicado: (2022)

Optimizing Clinical Trial Design to Maximize Evidence Generation in Pediatric HIV
por: Ford, Deborah, et al.
Publicado: (2018)

Impacts of timing, length, and intensity of behavioral interventions to COVID-19 dynamics: North Carolina county-level examples
por: Quiner, Claire, et al.
Publicado: (2022)

National polydrug use patterns among people who misuse prescription opioids and people who use heroin. Results from the National Household Survey on Drug Use and Health
por: Bobashev, Georgiy V., et al.
Publicado: (2022)

Combining Model‐Based Clinical Trial Simulation, Pharmacoeconomics, and Value of Information to Optimize Trial Design
por: Hill‐McManus, Daniel, et al.
Publicado: (2020)

Random forest methodology for model-based recursive partitioning: the mobForest package for R
por: Garge, Nikhil R, et al.
Publicado: (2013)

Predictive model of multiple emergency department visits among adults: analysis of the data from the National Survey of Drug Use and Health (NSDUH)
por: Bobashev, Georgiy, et al.
Publicado: (2021)

Trends in Opioid Misuse Among Individuals Aged 12 to 21 Years in the US
por: Warren, Lauren Klein, et al.
Publicado: (2023)

Sampling for Global Epidemic Models and the Topology of an International Airport Network
por: Bobashev, Georgiy, et al.
Publicado: (2008)

Are You HIV Invincible? A Probabilistic Study of Discordant Couples in the Context of HIV Transmission
por: Bobashev, Georgiy, et al.
Publicado: (2014)

Reducing the Complexity of an Agent-Based Local Heroin Market Model
por: Heard, Daniel, et al.
Publicado: (2014)

Text Analysis of Trends in Health Equity and Disparities From the Internal Revenue Service Tax Documentation Submitted by US Nonprofit Hospitals Between 2010 and 2019: Exploratory Study
por: Hadley, Emily, et al.
Publicado: (2023)

Towards clinical data-driven eligibility criteria optimization for interventional COVID-19 clinical trials
por: Kim, Jae Hyun, et al.
Publicado: (2020)

Evidence for the future – Designing a clinical trial
por: Hajebrahimi, Sakineh, et al.
Publicado: (2011)

Mosaicism in clinical genetics
por: Mefford, Heather C.
Publicado: (2021)

Questionnaires in clinical trials: guidelines for optimal design and administration
por: Edwards, Phil
Publicado: (2010)

Tutorial for $DESIGN in NONMEM: Clinical trial evaluation and optimization
por: Bauer, Robert J., et al.
Publicado: (2021)

Using Named Entity Recognition to Identify Substances Used in the Self-medication of Opioid Withdrawal: Natural Language Processing Study of Reddit Data
por: Preiss, Alexander, et al.
Publicado: (2022)

Modeling HIV transmission among persons who inject drugs (PWID) at the “End of the HIV Epidemic” and during the COVID-19 pandemic
por: Jarlais, Don Des, et al.
Publicado: (2022)

Multiscale modeling in the clinic: diseases of the brain and nervous system
por: Lytton, William W., et al.
Publicado: (2017)

Phase 0 clinical trials: towards a more complete ethics critique
por: Hill, T Patrick
Publicado: (2012)

The Optimal Management of Fistulizing Crohn’s Disease: Evidence beyond Randomized Clinical Trials
por: Wetwittayakhlang, Panu, et al.
Publicado: (2022)

Trends in mesenchymal stem cell clinical trials 2004‐2018: Is efficacy optimal in a narrow dose range?
por: Kabat, Maciej, et al.
Publicado: (2019)

Mosaic human preimplantation embryos and their developmental potential in a prospective, non-selection clinical trial
por: Capalbo, Antonio, et al.
Publicado: (2021)

Exploring Intervention Sustainment and Intervention Spread Following a Randomized Clinical Trial of the MOSAIC Program
por: Kassab, Hannah D., et al.
Publicado: (2023)

Optimal design for multi-arm multi-stage clinical trials
por: Wason, James MS, et al.
Publicado: (2011)

Optimal multistage designs for randomised clinical trials with continuous outcomes
por: Wason, James MS, et al.
Publicado: (2012)

Improvements in well-being and vagal tone following a yogic breathing-based life skills workshop in young adults: Two open-trial pilot studies
por: Goldstein, Michael R, et al.
Publicado: (2016)

Towards evidence-based computational statistics: lessons from clinical research on the role and design of real-data benchmark studies
por: Boulesteix, Anne-Laure, et al.
Publicado: (2017)

Feasibility of needle and syringe programs in Tajikistan distributing low dead space needles
por: Zule, William A., et al.
Publicado: (2018)

Heroin type, injecting behavior, and HIV transmission. A simulation model of HIV incidence and prevalence
por: Bobashev, Georgiy, et al.
Publicado: (2019)

Enhancing the prediction of hospitalization from a COVID-19 agent-based model: A Bayesian method for model parameter estimation
por: Hadley, Emily, et al.
Publicado: (2022)

Development of a model‐based clinical trial simulation platform to optimize the design of clinical trials for Duchenne muscular dystrophy
por: Lingineni, Karthik, et al.
Publicado: (2022)

Potential of Transcranial Direct Current Stimulation in Alzheimer’s Disease: Optimizing Trials Toward Clinical Use
por: Pilloni, Giuseppina, et al.
Publicado: (2022)

Clinical Outcomes of Single Mosaic Embryo Transfer: High-Level or Low-Level Mosaic Embryo, Does It Matter?
por: Lin, Pin-Yao, et al.
Publicado: (2020)

Evolution and optimization of clinical trial endpoints and design in pulmonary arterial hypertension
por: Caccamo, Marco, et al.
Publicado: (2023)

Moving towards clinical trials for mitochondrial diseases
por: Pitceathly, Robert D.S., et al.
Publicado: (2020)

Optimizing the study design of clinical trials to identify the efficacy of artificial intelligence tools in clinical practices
por: Zhou, Qian, et al.
Publicado: (2019)

Double jeopardy--drug and sex risks among Russian women who inject drugs: initial feasibility and efficacy results of a small randomized controlled trial
por: Wechsberg, Wendee M, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_a6q1k3fgv0ah75968627dvd3h8