Cargando…

Synergistic effect and ultrastructural changes in Trypanosoma cruzi caused by isoobtusilactone A in short exposure of time

Butanolides have shown a variety of biological effects including anti-inflammatory, antibacterial, and antiprotozoal effects against certain strains of Trypanosoma cruzi. Considering the lack of an effective drug to treat T. cruzi infections and the prominent results obtained in literature with this...

Descripción completa

Detalles Bibliográficos
Autores principales:	de Almeida, Júlio Menta, Nunes, Felipe Oliveira, Ceole, Lígia Fernanda, Klimeck, Tabata D’Maiella Freitas, da Cruz, Letícia Alves, Tófoli, Danilo, Borges, Beatriz Santana, Garcez, Walmir Silva, Tozetti, Inês Aparecida, Medeiros, Lia Carolina Soares, Garcez, Fernanda Rodrigues, Ferreira, Alda Maria Teixeira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842926/ https://www.ncbi.nlm.nih.gov/pubmed/33507972 http://dx.doi.org/10.1371/journal.pone.0245882

Ejemplares similares

Antitrypanosomal butanolides from Aiouea trinervis
por: Nunes, Felipe Oliveira, et al.
Publicado: (2020)

Cytotoxic and Apoptotic Activity of Majoranolide from Mezilaurus crassiramea on HL-60 Leukemia Cells
por: Heemann, Lanna M., et al.
Publicado: (2019)

Bioactive Pentacyclic Triterpenes from the Stems of Combretum laxum
por: Bisoli, Eder, et al.
Publicado: (2008)

Biological Synthesis of Low Cytotoxicity Silver Nanoparticles (AgNPs) by the Fungus Chaetomium thermophilum—Sustainable Nanotechnology
por: Alves, Mariana Fuinhas, et al.
Publicado: (2022)

Antiproliferative Effect and Ultrastructural Alterations Induced by Psilostachyin on Trypanosoma cruzi
por: Sülsen, Valeria, et al.
Publicado: (2010)

Evaluation of mutagenic and antimicrobial properties of brown propolis essential oil from the Brazilian Cerrado biome
por: Fernandes, Fábio H., et al.
Publicado: (2015)

Addition of α-O-GlcNAc to threonine residues define the post-translational modification of mucin-like molecules in Trypanosoma cruzi
por: Mendonça-Previato, Lucia, et al.
Publicado: (2013)

Antimicrobial activity of some medicinal plants from the cerrado of the centralwestern region of Brazil
por: Violante, Ivana Maria Póvoa, et al.
Publicado: (2012)

Effects of camptothecin derivatives and topoisomerase dual inhibitors on Trypanosoma cruzi growth and ultrastructure
por: Lacombe, Otto Kischlat, et al.
Publicado: (2014)

Revisiting the Trypanosoma cruzi metacyclogenesis: morphological and ultrastructural analyses during cell differentiation
por: Gonçalves, Camila Silva, et al.
Publicado: (2018)

Clathrin expression in Trypanosoma cruzi
por: Kalb, Ligia Cristina, et al.
Publicado: (2014)

3β-O-Tigloylmelianol from Guarea kunthiana: A New Potential Agent to Control Rhipicephalus (Boophilus) microplus, a Cattle Tick of Veterinary Significance
por: Miguita, Carlos Henrique, et al.
Publicado: (2014)

Acute heart inflammation: ultrastructural and functional aspects of macrophages elicited by Trypanosoma cruzi infection
por: Melo, Rossana C N
Publicado: (2009)

Emerging and reemerging forms of Trypanosoma cruzi transmission
por: Shikanai Yasuda, Maria Aparecida
Publicado: (2022)

Cytotoxic Phenanthrene, Dihydrophenanthrene, and Dihydrostilbene Derivatives and Other Aromatic Compounds from Combretum laxum
por: Bisoli, Eder, et al.
Publicado: (2020)

The Effectiveness of Natural Diarylheptanoids against Trypanosoma cruzi: Cytotoxicity, Ultrastructural Alterations and Molecular Modeling Studies
por: Sueth-Santiago, Vitor, et al.
Publicado: (2016)

The Impact of the CTHRSSVVC Peptide Upon Experimental Models of Trypanosoma cruzi Infection
por: Leite, Gabriela Rodrigues, et al.
Publicado: (2022)

Trypanin Disruption Affects the Motility and Infectivity of the Protozoan Trypanosoma cruzi
por: Saenz-Garcia, Jose L., et al.
Publicado: (2022)

DNA content analysis allows discrimination between Trypanosoma cruzi and Trypanosoma rangeli
por: Naves, Lucila Langoni, et al.
Publicado: (2017)

Wide distribution of Trypanosoma cruzi-infected triatomines in the State of Bahia, Brazil
por: Ribeiro, Gilmar, et al.
Publicado: (2019)

Review on Experimental Treatment Strategies Against Trypanosoma cruzi
por: Mazzeti, Ana Lia, et al.
Publicado: (2021)

In cellulo and in vivo assays for compound testing against Trypanosoma cruzi
por: Guerra-Slompo, Eloise Pavão, et al.
Publicado: (2023)

Conservation and divergence within the clathrin interactome of Trypanosoma cruzi
por: Kalb, Ligia Cristina, et al.
Publicado: (2016)

Effects of Infection by Trypanosoma cruzi and Trypanosoma rangeli on the Reproductive Performance of the Vector Rhodnius prolixus
por: Fellet, Maria Raquel, et al.
Publicado: (2014)

Immunopathological Aspects of Experimental Trypanosoma cruzi Reinfections
por: Reis Machado, Juliana, et al.
Publicado: (2014)

Development of an Aptamer-Based Concentration Method for the Detection of Trypanosoma cruzi in Blood
por: Nagarkatti, Rana, et al.
Publicado: (2012)

MDL28170, a Calpain Inhibitor, Affects Trypanosoma cruzi Metacyclogenesis, Ultrastructure and Attachment to Rhodnius prolixus Midgut
por: Ennes-Vidal, Vítor, et al.
Publicado: (2011)

Trypanosoma cruzi Infection in Neotropical Wild Carnivores (Mammalia: Carnivora): At the Top of the T. cruzi Transmission Chain
por: Rocha, Fabiana Lopes, et al.
Publicado: (2013)

Mode of Action of the Sesquiterpene Lactones Psilostachyin and Psilostachyin C on Trypanosoma cruzi
por: Sülsen, Valeria P., et al.
Publicado: (2016)

Profiling the Trypanosoma cruzi Phosphoproteome
por: Marchini, Fabricio K., et al.
Publicado: (2011)

Endothelial Transmigration by Trypanosoma cruzi
por: Coates, Bria M., et al.
Publicado: (2013)

The N-myristoylome of Trypanosoma cruzi
por: Roberts, Adam J., et al.
Publicado: (2016)

Larvicidal efficacies of plants from Midwestern Brazil: melianodiol from Guarea kunthiana as a potential biopesticide against Aedes aegypti
por: Sarmento, Ulana Chaves, et al.
Publicado: (2016)

Antimicrobial Potential of Essential Oils from Cerrado Plants against Multidrug−Resistant Foodborne Microorganisms
por: de Jesus, Genilson Silva, et al.
Publicado: (2020)

The Influence of Environmental Cues on the Development of Trypanosoma cruzi in Triatominae Vector
por: Melo, Raíssa de Fátima Pimentel, et al.
Publicado: (2020)

Oral Transmission of Trypanosoma cruzi, Brazilian Amazon
por: Santana, Rosa Amélia G., et al.
Publicado: (2019)

Interleukin-9 in Immunopathology of Trypanosoma cruzi Experimental Infection
por: Silva, Nadjania Saraiva de Lira, et al.
Publicado: (2021)

LM14 defined medium enables continuous growth of Trypanosoma cruzi
por: De Paula Lima, Carla V, et al.
Publicado: (2014)

Anti-parasitic effect of vitamin C alone and in combination with benznidazole against Trypanosoma cruzi
por: Puente, Vanesa, et al.
Publicado: (2018)

Outcome of E1224-Benznidazole Combination Treatment for Infection with a Multidrug-Resistant Trypanosoma cruzi Strain in Mice
por: Diniz, Lívia de Figueiredo, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ddtpt5lckn0vj5aj8q0n78qveu