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Highly exposed segment of the Spf1p P5A-ATPase near transmembrane M5 detected by limited proteolysis
The yeast Spf1p protein is a primary transporter that belongs to group 5 of the large family of P-ATPases. Loss of Spf1p function produces ER stress with alterations of metal ion and sterol homeostasis and protein folding, glycosylation and membrane insertion. The amino acid sequence of Spf1p shows...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842927/ https://www.ncbi.nlm.nih.gov/pubmed/33507968 http://dx.doi.org/10.1371/journal.pone.0245679 |