Cargando…

Real-time spatial health surveillance: Mapping the UK COVID-19 epidemic

Introduction The COVID-19 pandemic has highlighted the need for robust data linkage systems and methods for identifying outbreaks of disease in near real-time. Objectives The primary objective of this study was to develop a real-time geospatial surveillance system to monitor the spread of COVID-19 a...

Descripción completa

Detalles Bibliográficos
Autores principales: Fry, Richard, Hollinghurst, Joe, Stagg, Helen R, Thompson, Daniel A, Fronterre, Claudio, Orton, Chris, Lyons, Ronan A, Ford, David V, Sheikh, Aziz, Diggle, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ireland Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843148/
https://www.ncbi.nlm.nih.gov/pubmed/33667930
http://dx.doi.org/10.1016/j.ijmedinf.2021.104400
_version_ 1783644087712219136
author Fry, Richard
Hollinghurst, Joe
Stagg, Helen R
Thompson, Daniel A
Fronterre, Claudio
Orton, Chris
Lyons, Ronan A
Ford, David V
Sheikh, Aziz
Diggle, Peter J
author_facet Fry, Richard
Hollinghurst, Joe
Stagg, Helen R
Thompson, Daniel A
Fronterre, Claudio
Orton, Chris
Lyons, Ronan A
Ford, David V
Sheikh, Aziz
Diggle, Peter J
author_sort Fry, Richard
collection PubMed
description Introduction The COVID-19 pandemic has highlighted the need for robust data linkage systems and methods for identifying outbreaks of disease in near real-time. Objectives The primary objective of this study was to develop a real-time geospatial surveillance system to monitor the spread of COVID-19 across the UK. Methods Using self-reported app data and the Secure Anonymised Information Linkage (SAIL) Databank, we demonstrate the use of sophisticated spatial modelling for near-real-time prediction of COVID-19 prevalence at small-area resolution to inform strategic government policy areas. Results We demonstrate that using a combination of crowd-sourced app data and sophisticated geo-statistical techniques it is possible to predict hot spots of COVID-19 at fine geographic scales, nationally. We are also able to produce estimates of their precision, which is an important pre-requisite to an effective control strategy to guard against over-reaction to potentially spurious features of ’best guess’ predictions. Conclusion In the UK, important emerging risk-factors such as social deprivation or ethnicity vary over small distances, hence risk needs to be modelled at fine spatial resolution to avoid aggregation bias. We demonstrate that existing geospatial statistical methods originally developed for global health applications are well-suited to this task and can be used in an anonymised databank environment, thus preserving the privacy of the individuals who contribute their data.
format Online
Article
Text
id pubmed-7843148
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier Science Ireland Ltd
record_format MEDLINE/PubMed
spelling pubmed-78431482021-01-29 Real-time spatial health surveillance: Mapping the UK COVID-19 epidemic Fry, Richard Hollinghurst, Joe Stagg, Helen R Thompson, Daniel A Fronterre, Claudio Orton, Chris Lyons, Ronan A Ford, David V Sheikh, Aziz Diggle, Peter J Int J Med Inform Article Introduction The COVID-19 pandemic has highlighted the need for robust data linkage systems and methods for identifying outbreaks of disease in near real-time. Objectives The primary objective of this study was to develop a real-time geospatial surveillance system to monitor the spread of COVID-19 across the UK. Methods Using self-reported app data and the Secure Anonymised Information Linkage (SAIL) Databank, we demonstrate the use of sophisticated spatial modelling for near-real-time prediction of COVID-19 prevalence at small-area resolution to inform strategic government policy areas. Results We demonstrate that using a combination of crowd-sourced app data and sophisticated geo-statistical techniques it is possible to predict hot spots of COVID-19 at fine geographic scales, nationally. We are also able to produce estimates of their precision, which is an important pre-requisite to an effective control strategy to guard against over-reaction to potentially spurious features of ’best guess’ predictions. Conclusion In the UK, important emerging risk-factors such as social deprivation or ethnicity vary over small distances, hence risk needs to be modelled at fine spatial resolution to avoid aggregation bias. We demonstrate that existing geospatial statistical methods originally developed for global health applications are well-suited to this task and can be used in an anonymised databank environment, thus preserving the privacy of the individuals who contribute their data. Elsevier Science Ireland Ltd 2021-05 /pmc/articles/PMC7843148/ /pubmed/33667930 http://dx.doi.org/10.1016/j.ijmedinf.2021.104400 Text en Crown Copyright © 2021 Published by Elsevier B.V. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fry, Richard
Hollinghurst, Joe
Stagg, Helen R
Thompson, Daniel A
Fronterre, Claudio
Orton, Chris
Lyons, Ronan A
Ford, David V
Sheikh, Aziz
Diggle, Peter J
Real-time spatial health surveillance: Mapping the UK COVID-19 epidemic
title Real-time spatial health surveillance: Mapping the UK COVID-19 epidemic
title_full Real-time spatial health surveillance: Mapping the UK COVID-19 epidemic
title_fullStr Real-time spatial health surveillance: Mapping the UK COVID-19 epidemic
title_full_unstemmed Real-time spatial health surveillance: Mapping the UK COVID-19 epidemic
title_short Real-time spatial health surveillance: Mapping the UK COVID-19 epidemic
title_sort real-time spatial health surveillance: mapping the uk covid-19 epidemic
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843148/
https://www.ncbi.nlm.nih.gov/pubmed/33667930
http://dx.doi.org/10.1016/j.ijmedinf.2021.104400
work_keys_str_mv AT fryrichard realtimespatialhealthsurveillancemappingtheukcovid19epidemic
AT hollinghurstjoe realtimespatialhealthsurveillancemappingtheukcovid19epidemic
AT stagghelenr realtimespatialhealthsurveillancemappingtheukcovid19epidemic
AT thompsondaniela realtimespatialhealthsurveillancemappingtheukcovid19epidemic
AT fronterreclaudio realtimespatialhealthsurveillancemappingtheukcovid19epidemic
AT ortonchris realtimespatialhealthsurveillancemappingtheukcovid19epidemic
AT lyonsronana realtimespatialhealthsurveillancemappingtheukcovid19epidemic
AT forddavidv realtimespatialhealthsurveillancemappingtheukcovid19epidemic
AT sheikhaziz realtimespatialhealthsurveillancemappingtheukcovid19epidemic
AT digglepeterj realtimespatialhealthsurveillancemappingtheukcovid19epidemic