Simvastatin Inhibits CYR61 Expression in Orbital Fibroblasts in Graves' Ophthalmopathy through the Regulation of FoxO3a Signaling

Graves' ophthalmopathy (GO), which is characterized by orbital tissue inflammation, expansion, and fibrosis, is the ocular manifestation in 25% to 50% of patients with Graves' disease. As the pathology of GO is driven by autoimmune inflammation, many proinflammatory cytokines/chemokines, i...

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Detalles Bibliográficos
Autores principales: Wei, Yi-Hsuan, Liao, Shu-Lang, Wang, Chia-Chun, Wang, Sen-Hsu, Tang, Wan-Chun, Yang, Chang-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843182/
https://www.ncbi.nlm.nih.gov/pubmed/33542676
http://dx.doi.org/10.1155/2021/8888913

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