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Systemic Overexpression of GDF5 in Adipocytes but Not Hepatocytes Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver in Mice
OBJECTIVE: Our recent study demonstrated that growth differentiation factor 5 (GDF5) could promote white adipose tissue thermogenesis and alleviate high-fat diet- (HFD-) induced obesity in fatty acid-binding protein 4- (Fabp4-) GDF5 transgenic mice (TG). Here, we further investigated the effects of...
Autores principales: | Yang, Yan, Zhang, Wenting, Wu, Xiaohui, Wu, Jing, Sun, Chengjun, Luo, Feihong, Pei, Zhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843185/ https://www.ncbi.nlm.nih.gov/pubmed/33542911 http://dx.doi.org/10.1155/2021/8894685 |
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