An unbiased approach to defining bona fide cancer neoepitopes that elicit immune-mediated cancer rejection

Identification of neoepitopes that are effective in cancer therapy is a major challenge in creating cancer vaccines. Here, using an entirely unbiased approach, we queried all possible neoepitopes in a mouse cancer model and asked which of those are effective in mediating tumor rejection and, indepen...

Descripción completa

Detalles Bibliográficos
Autores principales: Brennick, Cory A., George, Mariam M., Moussa, Marmar M., Hagymasi, Adam T., Seesi, Sahar Al, Shcheglova, Tatiana V., Englander, Ryan P., Keller, Grant L.J., Balsbaugh, Jeremy L., Baker, Brian M., Schietinger, Andrea, Mandoiu, Ion I., Srivastava, Pramod K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843235/
https://www.ncbi.nlm.nih.gov/pubmed/33320837
http://dx.doi.org/10.1172/JCI142823

Ejemplares similares

Ejemplares similares