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Degradation of SARS-CoV-2 receptor ACE2 by the E3 ubiquitin ligase Skp2 in lung epithelial cells

An unexpected observation among the COVID-19 pandemic is that smokers constituted only 1.4%–18.5% of hospitalized adults, calling for an urgent investigation to determine the role of smoking in SARS-CoV-2 infection. Here, we show that cigarette smoke extract (CSE) and carcinogen benzo(a)pyrene (BaP)...

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Detalles Bibliográficos
Autores principales:	Wang, Guizhen, Zhao, Qun, Zhang, Hui, Liang, Fan, Zhang, Chen, Wang, Jun, Chen, Zhenyin, Wu, Ran, Yu, Hong, Sun, Beibei, Guo, Hua, Feng, Ruie, Xu, Kaifeng, Zhou, Guangbiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Higher Education Press 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843238/ https://www.ncbi.nlm.nih.gov/pubmed/33511555 http://dx.doi.org/10.1007/s11684-021-0837-6

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