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Studies on the serological markers for hepatitis B virus infection among type 2 diabetic patients

BACKGROUND: Hepatitis B infection is a public health concern globally. HBV can be associated with type II diabetes mellitus, as HBV outbreaks have been observed among diabetics in healthcare facilities. This study evaluates the prevalence of HBV infection among patients with type II diabetes mellitu...

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Autores principales: Ndako, James A., Nwankiti, Obinna O., Olorundare, Joy O., Ojo, Stephen K.S., Okolie, Charles E., Olatinsu, Oludolapo, Dojumo, Victor T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843284/
https://www.ncbi.nlm.nih.gov/pubmed/33410548
http://dx.doi.org/10.1002/jcla.23464
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author Ndako, James A.
Nwankiti, Obinna O.
Olorundare, Joy O.
Ojo, Stephen K.S.
Okolie, Charles E.
Olatinsu, Oludolapo
Dojumo, Victor T.
author_facet Ndako, James A.
Nwankiti, Obinna O.
Olorundare, Joy O.
Ojo, Stephen K.S.
Okolie, Charles E.
Olatinsu, Oludolapo
Dojumo, Victor T.
author_sort Ndako, James A.
collection PubMed
description BACKGROUND: Hepatitis B infection is a public health concern globally. HBV can be associated with type II diabetes mellitus, as HBV outbreaks have been observed among diabetics in healthcare facilities. This study evaluates the prevalence of HBV infection among patients with type II diabetes mellitus. METHOD: A total of one hundred and eighty (180) diabetic patients and one‐hundred non‐diabetics (Controls) were recruited for this study. Structured questionnaires were administered to the consented participants to obtain relevant data. Sera samples obtained were screened using the HBsAg ELISA kit; CTK Biotech, Inc, while the 5 panel kit—rapid diagnostic test, was used to assay for serological markers. Questionnaires were used to obtain relevant information and demographic data. RESULT: Overall prevalence of HBV infection among diabetes patients was 13.3%. Breakdown showed 9 (5.0%) seropositivity was obtained among male subjects compared to 15(8.3%) recorded among the females, P = .834; P < .05. Subjects aged 41‐50 years recorded, 7(3.9%) positivity P = .774; P > .05. Educational status of participants showed 22 (12.2%) positivity among subjects with tertiary level of education P = .032; P < .05). Risk factors considered showed that 5(2.8%).seropositive subjects were alcoholic consumers (P value = .9711; P > .05). Result among non‐diabetics (Control) subjects showed (4%) seropositivity among the male subjects compared to (5.0%) seropositivity recorded among the female subjects (P = .739; P > .05). CONCLUSION: There is an indication of higher risk of HBV infection among type 2 diabetic patients when compared to non‐diabetics. There is the need for more research on this area of study, to further validate the association between HBV infection and Diabetes Mellitus.
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spelling pubmed-78432842021-02-02 Studies on the serological markers for hepatitis B virus infection among type 2 diabetic patients Ndako, James A. Nwankiti, Obinna O. Olorundare, Joy O. Ojo, Stephen K.S. Okolie, Charles E. Olatinsu, Oludolapo Dojumo, Victor T. J Clin Lab Anal Research Articles BACKGROUND: Hepatitis B infection is a public health concern globally. HBV can be associated with type II diabetes mellitus, as HBV outbreaks have been observed among diabetics in healthcare facilities. This study evaluates the prevalence of HBV infection among patients with type II diabetes mellitus. METHOD: A total of one hundred and eighty (180) diabetic patients and one‐hundred non‐diabetics (Controls) were recruited for this study. Structured questionnaires were administered to the consented participants to obtain relevant data. Sera samples obtained were screened using the HBsAg ELISA kit; CTK Biotech, Inc, while the 5 panel kit—rapid diagnostic test, was used to assay for serological markers. Questionnaires were used to obtain relevant information and demographic data. RESULT: Overall prevalence of HBV infection among diabetes patients was 13.3%. Breakdown showed 9 (5.0%) seropositivity was obtained among male subjects compared to 15(8.3%) recorded among the females, P = .834; P < .05. Subjects aged 41‐50 years recorded, 7(3.9%) positivity P = .774; P > .05. Educational status of participants showed 22 (12.2%) positivity among subjects with tertiary level of education P = .032; P < .05). Risk factors considered showed that 5(2.8%).seropositive subjects were alcoholic consumers (P value = .9711; P > .05). Result among non‐diabetics (Control) subjects showed (4%) seropositivity among the male subjects compared to (5.0%) seropositivity recorded among the female subjects (P = .739; P > .05). CONCLUSION: There is an indication of higher risk of HBV infection among type 2 diabetic patients when compared to non‐diabetics. There is the need for more research on this area of study, to further validate the association between HBV infection and Diabetes Mellitus. John Wiley and Sons Inc. 2021-01-07 /pmc/articles/PMC7843284/ /pubmed/33410548 http://dx.doi.org/10.1002/jcla.23464 Text en © 2021 The Authors. Journal of Clinical Laboratory Analysis Published by Wiley Periodicals LLC. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Ndako, James A.
Nwankiti, Obinna O.
Olorundare, Joy O.
Ojo, Stephen K.S.
Okolie, Charles E.
Olatinsu, Oludolapo
Dojumo, Victor T.
Studies on the serological markers for hepatitis B virus infection among type 2 diabetic patients
title Studies on the serological markers for hepatitis B virus infection among type 2 diabetic patients
title_full Studies on the serological markers for hepatitis B virus infection among type 2 diabetic patients
title_fullStr Studies on the serological markers for hepatitis B virus infection among type 2 diabetic patients
title_full_unstemmed Studies on the serological markers for hepatitis B virus infection among type 2 diabetic patients
title_short Studies on the serological markers for hepatitis B virus infection among type 2 diabetic patients
title_sort studies on the serological markers for hepatitis b virus infection among type 2 diabetic patients
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843284/
https://www.ncbi.nlm.nih.gov/pubmed/33410548
http://dx.doi.org/10.1002/jcla.23464
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