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Effects of modified lipoproteins on human trophoblast cells: a role in pre-eclampsia in pregnancies complicated by diabetes

INTRODUCTION: Pre-eclampsia (PE) is increased ~4-fold by maternal diabetes. Elevated plasma antiangiogenic factors, soluble fms-like tyrosine kinase (sFLT-1) and soluble endoglin (sENG), precede PE onset. We investigated whether diabetes-related stresses, modified lipoproteins and elevated glucose e...

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Detalles Bibliográficos
Autores principales: McLeese, Rebecca Helen, Zhao, Jiawu, Fu, Dongxu, Yu, Jeremy Y, Brazil, Derek P, Lyons, Timothy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843297/
https://www.ncbi.nlm.nih.gov/pubmed/33504507
http://dx.doi.org/10.1136/bmjdrc-2020-001696