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ACE2 gene transfer ameliorates vasoreparative dysfunction in CD34(+) cells derived from diabetic older adults

Diabetes increases the risk for ischemic vascular diseases, which is further elevated in older adults. Bone marrow-derived hematopoietic CD34(+) stem/progenitor cells have the potential of revascularization; however, diabetes attenuates vasoreparative functions. Angiotensin-converting enzyme 2 (ACE2...

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Detalles Bibliográficos
Autores principales: Joshi, Shrinidh, Montes de Oca, Ildamaris, Maghrabi, Ahmad, Lopez-Yang, Christine, Quiroz-Olvera, Julio, Garcia, Charles A., Jarajapu, Yagna Prasada Rao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843404/
https://www.ncbi.nlm.nih.gov/pubmed/33409538
http://dx.doi.org/10.1042/CS20201133

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