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Basolateral activation with TLR agonists induces polarized cytokine release and reduces barrier function in RPE in vitro
PURPOSE: Systemic inflammation may be of importance in the development of AMD. RPE cells can recognize danger signals with toll-like receptors (TLR) and may react in a pro-inflammatory manner. In this study, we evaluated the basal and apical secretions of TNFα, IL-6, and IL-1β in primary RPE cells a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843481/ https://www.ncbi.nlm.nih.gov/pubmed/32949301 http://dx.doi.org/10.1007/s00417-020-04930-2 |