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Microfluidic ratio metering devices fabricated in PMMA by CO(2) laser

We describe microfluidic fabrication results achieved using a 10.6 μm CO(2) engraving laser on cast PMMA, in both raster and vector mode, with a 1.5″ lens and a High Power Density Focussing Optics lens. Raster written channels show a flatter base and are more U-shaped, while vector written channels...

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Autores principales: Tweedie, M., Maguire, P. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843490/
https://www.ncbi.nlm.nih.gov/pubmed/33551575
http://dx.doi.org/10.1007/s00542-020-04902-w
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author Tweedie, M.
Maguire, P. D.
author_facet Tweedie, M.
Maguire, P. D.
author_sort Tweedie, M.
collection PubMed
description We describe microfluidic fabrication results achieved using a 10.6 μm CO(2) engraving laser on cast PMMA, in both raster and vector mode, with a 1.5″ lens and a High Power Density Focussing Optics lens. Raster written channels show a flatter base and are more U-shaped, while vector written channels are V shaped. Cross-sectional images, and, where possible, stylus profilometry results are presented. The sides of V-grooves become increasing steep with laser power, but broader shallower channels may be produced in vector mode by laser defocus, as illustrated. Smoothing of raster engraved channels by heated IPA etch, and transparency enhancement by CHCl(3) vapour treatment are briefly discussed. An asymmetric Y meter is discussed as one method of diluting acid into seawater for dissolved CO(2) analysis. Alternatively, microfluidic snake channel restrictors of different lengths in 2 channels may achieve the same result. Samples are fabricated with bases bonded by CHCl(3) vapour treatment, and the devices are flow tested with either dilute food dye or DI water. Microfluidics fabricated in this manner have applications in ocean sensing of dissolved CO(2) and other analytes, as well as broader sensing measurements, including biomedical sensors.
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spelling pubmed-78434902021-02-04 Microfluidic ratio metering devices fabricated in PMMA by CO(2) laser Tweedie, M. Maguire, P. D. Microsyst Technol Technical Paper We describe microfluidic fabrication results achieved using a 10.6 μm CO(2) engraving laser on cast PMMA, in both raster and vector mode, with a 1.5″ lens and a High Power Density Focussing Optics lens. Raster written channels show a flatter base and are more U-shaped, while vector written channels are V shaped. Cross-sectional images, and, where possible, stylus profilometry results are presented. The sides of V-grooves become increasing steep with laser power, but broader shallower channels may be produced in vector mode by laser defocus, as illustrated. Smoothing of raster engraved channels by heated IPA etch, and transparency enhancement by CHCl(3) vapour treatment are briefly discussed. An asymmetric Y meter is discussed as one method of diluting acid into seawater for dissolved CO(2) analysis. Alternatively, microfluidic snake channel restrictors of different lengths in 2 channels may achieve the same result. Samples are fabricated with bases bonded by CHCl(3) vapour treatment, and the devices are flow tested with either dilute food dye or DI water. Microfluidics fabricated in this manner have applications in ocean sensing of dissolved CO(2) and other analytes, as well as broader sensing measurements, including biomedical sensors. Springer Berlin Heidelberg 2020-06-01 2021 /pmc/articles/PMC7843490/ /pubmed/33551575 http://dx.doi.org/10.1007/s00542-020-04902-w Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Technical Paper
Tweedie, M.
Maguire, P. D.
Microfluidic ratio metering devices fabricated in PMMA by CO(2) laser
title Microfluidic ratio metering devices fabricated in PMMA by CO(2) laser
title_full Microfluidic ratio metering devices fabricated in PMMA by CO(2) laser
title_fullStr Microfluidic ratio metering devices fabricated in PMMA by CO(2) laser
title_full_unstemmed Microfluidic ratio metering devices fabricated in PMMA by CO(2) laser
title_short Microfluidic ratio metering devices fabricated in PMMA by CO(2) laser
title_sort microfluidic ratio metering devices fabricated in pmma by co(2) laser
topic Technical Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843490/
https://www.ncbi.nlm.nih.gov/pubmed/33551575
http://dx.doi.org/10.1007/s00542-020-04902-w
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