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Hypoxic stress increases NF-κB and iNOS mRNA expression in normal, but not in keratoconus corneal fibroblasts

BACKGROUND: Keratoconus (KC) is associated with oxidative stress and hypoxia and as several times discussed, potentially with inflammatory components. Inflammation, hypoxia, and oxidative stress may result in metabolic dysfunction and are directly linked to each other. In the current study, we inves...

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Detalles Bibliográficos
Autores principales: Stachon, Tanja, Latta, Lorenz, Seitz, Berthold, Szentmáry, Nóra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843574/
https://www.ncbi.nlm.nih.gov/pubmed/32886165
http://dx.doi.org/10.1007/s00417-020-04900-8