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Transient Receptor Potential Channel 6 Knockout Ameliorates Kidney Fibrosis by Inhibition of Epithelial–Mesenchymal Transition

Kidney fibrosis is generally confirmed to have a significant role in chronic kidney disease, resulting in end-stage kidney failure. Epithelial–mesenchymal transition (EMT) is an important molecular mechanism contributing to fibrosis. Tubular epithelial cells (TEC), the major component of kidney pare...

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Detalles Bibliográficos
Autores principales: Zhang, Yanhong, Yin, Nina, Sun, Anbang, Wu, Qifang, Hu, Wenzhu, Hou, Xin, Zeng, Xixi, Zhu, Min, Liao, Yanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843578/
https://www.ncbi.nlm.nih.gov/pubmed/33520986
http://dx.doi.org/10.3389/fcell.2020.602703