Cargando…
Identification of triptonide as a therapeutic agent for triple negative breast cancer treatment
Triple-negative breast cancer (TNBC) is associated with a high rate of early recurrence and distant metastasis, frequent development of therapeutic resistance, and a poor prognosis. There is a lack of targeted therapies for this aggressive subtype of breast cancer. Identifying novel effective treatm...
Autores principales: | Gao, Bowen, Chen, Jiongyu, Han, Bingchen, Zhang, Xinfeng, Hao, Jijun, Giuliano, Armando E., Cui, Yukun, Cui, Xiaojiang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843598/ https://www.ncbi.nlm.nih.gov/pubmed/33510281 http://dx.doi.org/10.1038/s41598-021-82128-0 |
Ejemplares similares
-
Breast cancer lung metastasis: Molecular biology and therapeutic implications
por: Jin, Liting, et al.
Publicado: (2018) -
FOXC1-Induced Non-Canonical WNT5A-MMP7 Signaling Regulates Invasiveness in Triple-Negative Breast Cancer
por: Han, Bingchen, et al.
Publicado: (2017) -
Triptonide effectively inhibits triple-negative breast cancer metastasis through concurrent degradation of Twist1 and Notch1 oncoproteins
por: Zhang, Mengli, et al.
Publicado: (2021) -
Identification of EGF-NF-κB-FOXC1 signaling axis in basal-like breast cancer
por: Chung, Stacey, et al.
Publicado: (2017) -
A chemokine regulatory loop induces cholesterol synthesis in lung-colonizing triple-negative breast cancer cells to fuel metastatic growth
por: Han, Bingchen, et al.
Publicado: (2022)