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MicroRNA‑331 inhibits isoproterenol‑induced expression of profibrotic genes in cardiac myofibroblasts via the TGFβ/smad3 signaling pathway

Cardiac fibrosis in the failing heart is modulated by activated myofibroblasts, and is a pathology marked by their deposition of extracellular matrix proteins. The TGFβ signaling pathway is important in stimulating fibrosis and therefore seems an attractive new target for anti-fibrotic therapy. The...

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Detalles Bibliográficos
Autores principales:	Yousefi, Fatemeh, Soltani, Bahram M., Rabbani, Shahram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843612/ https://www.ncbi.nlm.nih.gov/pubmed/33510328 http://dx.doi.org/10.1038/s41598-021-82226-z

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