Surfactant protein A reduces TLR4 and inflammatory cytokine mRNA levels in neonatal mouse ileum

Levels of intestinal toll-like receptor 4 (TLR4) impact inflammation in the neonatal gastrointestinal tract. While surfactant protein A (SP-A) is known to regulate TLR4 in the lung, it also reduces intestinal damage, TLR4 and inflammation in an experimental model of necrotizing enterocolitis (NEC) i...

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Detalles Bibliográficos
Autores principales: Liu, Lidan, Aron, Chaim Z., Grable, Cullen M., Robles, Adrian, Liu, Xiangli, Liu, Yuying, Fatheree, Nicole Y., Rhoads, J. Marc, Alcorn, Joseph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843620/
https://www.ncbi.nlm.nih.gov/pubmed/33510368
http://dx.doi.org/10.1038/s41598-021-82219-y

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