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Central aortic hemodynamics following acute lower and upper-body exercise in a cold environment among patients with coronary artery disease
Exercise is beneficial to cardiovascular health, evidenced by reduced post-exercise central aortic blood pressure (BP) and wave reflection. We assessed if post-exercise central hemodynamics are modified due to an altered thermal state related to exercise in the cold in patients with coronary artery...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843633/ https://www.ncbi.nlm.nih.gov/pubmed/33510373 http://dx.doi.org/10.1038/s41598-021-82155-x |
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author | Hintsala, Heidi E. Valtonen, Rasmus I. P. Kiviniemi, Antti Crandall, Craig Perkiömäki, Juha Hautala, Arto Mäntysaari, Matti Alén, Markku Ryti, Niilo Jaakkola, Jouni J. K. Ikäheimo, Tiina M. |
author_facet | Hintsala, Heidi E. Valtonen, Rasmus I. P. Kiviniemi, Antti Crandall, Craig Perkiömäki, Juha Hautala, Arto Mäntysaari, Matti Alén, Markku Ryti, Niilo Jaakkola, Jouni J. K. Ikäheimo, Tiina M. |
author_sort | Hintsala, Heidi E. |
collection | PubMed |
description | Exercise is beneficial to cardiovascular health, evidenced by reduced post-exercise central aortic blood pressure (BP) and wave reflection. We assessed if post-exercise central hemodynamics are modified due to an altered thermal state related to exercise in the cold in patients with coronary artery disease (CAD). CAD patients (n = 11) performed moderate-intensity lower-body exercise (walking at 65–70% of HR(max)) and rested in neutral (+ 22 °C) and cold (− 15 °C) conditions. In another protocol, CAD patients (n = 15) performed static (five 1.5 min work cycles, 10–30% of maximal voluntary contraction) and dynamic (three 5 min workloads, 56–80% of HR(max)) upper-body exercise at the same temperatures. Both datasets consisted of four 30-min exposures administered in random order. Central aortic BP and augmentation index (AI) were noninvasively assessed via pulse wave analyses prior to and 25 min after these interventions. Lower-body dynamic exercise decreased post-exercise central systolic BP (6–10 mmHg, p < 0.001) and AI (1–6%, p < 0.001) both after cold and neutral and conditions. Dynamic upper-body exercise lowered central systolic BP (2–4 mmHg, p < 0.001) after exposure to both temperatures. In contrast, static upper-body exercise increased central systolic BP after exposure to cold (7 ± 6 mmHg, p < 0.001). Acute dynamic lower and upper-body exercise mainly lowers post-exercise central BP in CAD patients irrespective of the environmental temperature. In contrast, central systolic BP was elevated after static exercise in cold. CAD patients likely benefit from year-round dynamic exercise, but hemodynamic responses following static exercise in a cold environment should be examined further. Clinical trials.gov: NCT02855905 04/08/2016. |
format | Online Article Text |
id | pubmed-7843633 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-78436332021-01-29 Central aortic hemodynamics following acute lower and upper-body exercise in a cold environment among patients with coronary artery disease Hintsala, Heidi E. Valtonen, Rasmus I. P. Kiviniemi, Antti Crandall, Craig Perkiömäki, Juha Hautala, Arto Mäntysaari, Matti Alén, Markku Ryti, Niilo Jaakkola, Jouni J. K. Ikäheimo, Tiina M. Sci Rep Article Exercise is beneficial to cardiovascular health, evidenced by reduced post-exercise central aortic blood pressure (BP) and wave reflection. We assessed if post-exercise central hemodynamics are modified due to an altered thermal state related to exercise in the cold in patients with coronary artery disease (CAD). CAD patients (n = 11) performed moderate-intensity lower-body exercise (walking at 65–70% of HR(max)) and rested in neutral (+ 22 °C) and cold (− 15 °C) conditions. In another protocol, CAD patients (n = 15) performed static (five 1.5 min work cycles, 10–30% of maximal voluntary contraction) and dynamic (three 5 min workloads, 56–80% of HR(max)) upper-body exercise at the same temperatures. Both datasets consisted of four 30-min exposures administered in random order. Central aortic BP and augmentation index (AI) were noninvasively assessed via pulse wave analyses prior to and 25 min after these interventions. Lower-body dynamic exercise decreased post-exercise central systolic BP (6–10 mmHg, p < 0.001) and AI (1–6%, p < 0.001) both after cold and neutral and conditions. Dynamic upper-body exercise lowered central systolic BP (2–4 mmHg, p < 0.001) after exposure to both temperatures. In contrast, static upper-body exercise increased central systolic BP after exposure to cold (7 ± 6 mmHg, p < 0.001). Acute dynamic lower and upper-body exercise mainly lowers post-exercise central BP in CAD patients irrespective of the environmental temperature. In contrast, central systolic BP was elevated after static exercise in cold. CAD patients likely benefit from year-round dynamic exercise, but hemodynamic responses following static exercise in a cold environment should be examined further. Clinical trials.gov: NCT02855905 04/08/2016. Nature Publishing Group UK 2021-01-28 /pmc/articles/PMC7843633/ /pubmed/33510373 http://dx.doi.org/10.1038/s41598-021-82155-x Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Hintsala, Heidi E. Valtonen, Rasmus I. P. Kiviniemi, Antti Crandall, Craig Perkiömäki, Juha Hautala, Arto Mäntysaari, Matti Alén, Markku Ryti, Niilo Jaakkola, Jouni J. K. Ikäheimo, Tiina M. Central aortic hemodynamics following acute lower and upper-body exercise in a cold environment among patients with coronary artery disease |
title | Central aortic hemodynamics following acute lower and upper-body exercise in a cold environment among patients with coronary artery disease |
title_full | Central aortic hemodynamics following acute lower and upper-body exercise in a cold environment among patients with coronary artery disease |
title_fullStr | Central aortic hemodynamics following acute lower and upper-body exercise in a cold environment among patients with coronary artery disease |
title_full_unstemmed | Central aortic hemodynamics following acute lower and upper-body exercise in a cold environment among patients with coronary artery disease |
title_short | Central aortic hemodynamics following acute lower and upper-body exercise in a cold environment among patients with coronary artery disease |
title_sort | central aortic hemodynamics following acute lower and upper-body exercise in a cold environment among patients with coronary artery disease |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843633/ https://www.ncbi.nlm.nih.gov/pubmed/33510373 http://dx.doi.org/10.1038/s41598-021-82155-x |
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