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Approximate conditional phenotype analysis based on genome wide association summary statistics

Because single genetic variants may have pleiotropic effects, one trait can be a confounder in a genome-wide association study (GWAS) that aims to identify loci associated with another trait. A typical approach to address this issue is to perform an additional analysis adjusting for the confounder....

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Detalles Bibliográficos
Autores principales:	Wu, Peitao, Wang, Biqi, Lubitz, Steven A., Benjamin, Emelia J., Meigs, James B., Dupuis, Josée
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843738/ https://www.ncbi.nlm.nih.gov/pubmed/33510268 http://dx.doi.org/10.1038/s41598-021-82000-1

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