Cargando…
The Molecular Mechanism of Chronic High-Dose Corticosterone-Induced Aggravation of Cognitive Impairment in APP/PS1 Transgenic Mice
Clinical studies have found that some Alzheimer’s disease (AD) patients suffer from Cushing’s syndrome (CS). CS is caused by the long-term release of excess glucocorticoids (GCs) from the adrenal gland, which in turn, impair brain function and induce dementia. Thus, we investigated the mechanism of...
Autores principales: | Zhang, Shen-Qing, Cao, Long-Long, Liang, Yun-Yue, Wang, Pu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844096/ https://www.ncbi.nlm.nih.gov/pubmed/33519376 http://dx.doi.org/10.3389/fnmol.2020.613421 |
Ejemplares similares
-
Naringin Dihydrochalcone Ameliorates Cognitive Deficits and Neuropathology in APP/PS1 Transgenic Mice
por: Yang, Wenjuan, et al.
Publicado: (2018) -
Exposure to fluoride aggravates the impairment in learning and memory and neuropathological lesions in mice carrying the APP/PS1 double-transgenic mutation
por: Cao, Kun, et al.
Publicado: (2019) -
Effects of (−)Epicatechin on the Pathology of APP/PS1 Transgenic Mice
por: Zeng, Yue-Qin, et al.
Publicado: (2014) -
Neuropeptide S Ameliorates Cognitive Impairment of APP/PS1 Transgenic Mice by Promoting Synaptic Plasticity and Reducing Aβ Deposition
por: Zhao, Peng, et al.
Publicado: (2019) -
Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites
por: Yan, Yuqing, et al.
Publicado: (2021)