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Novel Phosphorylation-State Specific Antibodies Reveal Differential Deposition of Ser26 Phosphorylated Aβ Species in a Mouse Model of Alzheimer’s Disease
Aggregation and deposition of amyloid-β (Aβ) peptides in extracellular plaques and in the cerebral vasculature are prominent neuropathological features of Alzheimer’s disease (AD) and closely associated with the pathogenesis of AD. Amyloid plaques in the brains of most AD patients and transgenic mou...
Autores principales: | Kumar, Sathish, Kapadia, Akshay, Theil, Sandra, Joshi, Pranav, Riffel, Florian, Heneka, Michael T., Walter, Jochen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844098/ https://www.ncbi.nlm.nih.gov/pubmed/33519377 http://dx.doi.org/10.3389/fnmol.2020.619639 |
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