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Strong Binding of Leupeptin with TMPRSS2 Protease May Be an Alternative to Camostat and Nafamostat for SARS-CoV-2 Repurposed Drug: Evaluation from Molecular Docking and Molecular Dynamics Simulations
The unprecedented coronavirus SARS-CoV-2 outbreak at Wuhan, China, caused acute respiratory infection to humans. There is no precise vaccine/therapeutic agents available to combat the COVID-19 disease. Some repurposed drugs are saving the life of diseased, but the complete cure is relatively less. S...
Autores principales: | Ramakrishnan, Jaganathan, Kandasamy, Saravanan, Iruthayaraj, Ancy, Magudeeswaran, Sivanandam, Chinnasamy, Kalaiarasi, Poomani, Kumaradhas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844105/ https://www.ncbi.nlm.nih.gov/pubmed/33512650 http://dx.doi.org/10.1007/s12010-020-03475-8 |
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