Long non-coding RNA Meg3 deficiency impairs glucose homeostasis and insulin signaling by inducing cellular senescence of hepatic endothelium in obesity

Obesity-induced insulin resistance is a risk factor for diabetes and cardiovascular disease. However, the mechanisms underlying endothelial senescence in obesity, and how it impacts obesity-induced insulin resistance remain incompletely understood. In this study, transcriptome analysis revealed that...

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Detalles Bibliográficos
Autores principales: Cheng, Xiao, Shihabudeen Haider Ali, Mohamed Sham, Moran, Matthew, Viana, Martonio Ponte, Schlichte, Sarah L., Zimmerman, Matthew C., Khalimonchuk, Oleh, Feinberg, Mark W., Sun, Xinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844131/
https://www.ncbi.nlm.nih.gov/pubmed/33508742
http://dx.doi.org/10.1016/j.redox.2021.101863

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