Particulate matter (PM(2.5)) as a potential SARS-CoV-2 carrier

The rapid spread of the SARS-CoV-2 in the COVID-19 pandemic had raised questions on the route of transmission of this disease. Initial understanding was that transmission originated from respiratory droplets from an infected host to a susceptible host. However, indirect contact transmission of viabl...

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Autores principales: Nor, Norefrina Shafinaz Md, Yip, Chee Wai, Ibrahim, Nazlina, Jaafar, Mohd Hasni, Rashid, Zetti Zainol, Mustafa, Norlaila, Hamid, Haris Hafizal Abd, Chandru, Kuhan, Latif, Mohd Talib, Saw, Phei Er, Lin, Chin Yik, Alhasa, Kemal Maulana, Hashim, Jamal Hisham, Nadzir, Mohd Shahrul Mohd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844283/
https://www.ncbi.nlm.nih.gov/pubmed/33510270
http://dx.doi.org/10.1038/s41598-021-81935-9
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author Nor, Norefrina Shafinaz Md
Yip, Chee Wai
Ibrahim, Nazlina
Jaafar, Mohd Hasni
Rashid, Zetti Zainol
Mustafa, Norlaila
Hamid, Haris Hafizal Abd
Chandru, Kuhan
Latif, Mohd Talib
Saw, Phei Er
Lin, Chin Yik
Alhasa, Kemal Maulana
Hashim, Jamal Hisham
Nadzir, Mohd Shahrul Mohd
author_facet Nor, Norefrina Shafinaz Md
Yip, Chee Wai
Ibrahim, Nazlina
Jaafar, Mohd Hasni
Rashid, Zetti Zainol
Mustafa, Norlaila
Hamid, Haris Hafizal Abd
Chandru, Kuhan
Latif, Mohd Talib
Saw, Phei Er
Lin, Chin Yik
Alhasa, Kemal Maulana
Hashim, Jamal Hisham
Nadzir, Mohd Shahrul Mohd
author_sort Nor, Norefrina Shafinaz Md
collection PubMed
description The rapid spread of the SARS-CoV-2 in the COVID-19 pandemic had raised questions on the route of transmission of this disease. Initial understanding was that transmission originated from respiratory droplets from an infected host to a susceptible host. However, indirect contact transmission of viable virus by fomites and through aerosols has also been suggested. Herein, we report the involvement of fine indoor air particulates with a diameter of ≤ 2.5 µm (PM(2.5)) as the virus’s transport agent. PM(2.5) was collected over four weeks during 48-h measurement intervals in four separate hospital wards containing different infected clusters in a teaching hospital in Kuala Lumpur, Malaysia. Our results indicated the highest SARS-CoV-2 RNA on PM(2.5) in the ward with number of occupants. We suggest a link between the virus-laden PM(2.5) and the ward’s design. Patients’ symptoms and numbers influence the number of airborne SARS-CoV-2 RNA with PM(2.5) in an enclosed environment.
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spelling pubmed-78442832021-02-01 Particulate matter (PM(2.5)) as a potential SARS-CoV-2 carrier Nor, Norefrina Shafinaz Md Yip, Chee Wai Ibrahim, Nazlina Jaafar, Mohd Hasni Rashid, Zetti Zainol Mustafa, Norlaila Hamid, Haris Hafizal Abd Chandru, Kuhan Latif, Mohd Talib Saw, Phei Er Lin, Chin Yik Alhasa, Kemal Maulana Hashim, Jamal Hisham Nadzir, Mohd Shahrul Mohd Sci Rep Article The rapid spread of the SARS-CoV-2 in the COVID-19 pandemic had raised questions on the route of transmission of this disease. Initial understanding was that transmission originated from respiratory droplets from an infected host to a susceptible host. However, indirect contact transmission of viable virus by fomites and through aerosols has also been suggested. Herein, we report the involvement of fine indoor air particulates with a diameter of ≤ 2.5 µm (PM(2.5)) as the virus’s transport agent. PM(2.5) was collected over four weeks during 48-h measurement intervals in four separate hospital wards containing different infected clusters in a teaching hospital in Kuala Lumpur, Malaysia. Our results indicated the highest SARS-CoV-2 RNA on PM(2.5) in the ward with number of occupants. We suggest a link between the virus-laden PM(2.5) and the ward’s design. Patients’ symptoms and numbers influence the number of airborne SARS-CoV-2 RNA with PM(2.5) in an enclosed environment. Nature Publishing Group UK 2021-01-28 /pmc/articles/PMC7844283/ /pubmed/33510270 http://dx.doi.org/10.1038/s41598-021-81935-9 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Nor, Norefrina Shafinaz Md
Yip, Chee Wai
Ibrahim, Nazlina
Jaafar, Mohd Hasni
Rashid, Zetti Zainol
Mustafa, Norlaila
Hamid, Haris Hafizal Abd
Chandru, Kuhan
Latif, Mohd Talib
Saw, Phei Er
Lin, Chin Yik
Alhasa, Kemal Maulana
Hashim, Jamal Hisham
Nadzir, Mohd Shahrul Mohd
Particulate matter (PM(2.5)) as a potential SARS-CoV-2 carrier
title Particulate matter (PM(2.5)) as a potential SARS-CoV-2 carrier
title_full Particulate matter (PM(2.5)) as a potential SARS-CoV-2 carrier
title_fullStr Particulate matter (PM(2.5)) as a potential SARS-CoV-2 carrier
title_full_unstemmed Particulate matter (PM(2.5)) as a potential SARS-CoV-2 carrier
title_short Particulate matter (PM(2.5)) as a potential SARS-CoV-2 carrier
title_sort particulate matter (pm(2.5)) as a potential sars-cov-2 carrier
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844283/
https://www.ncbi.nlm.nih.gov/pubmed/33510270
http://dx.doi.org/10.1038/s41598-021-81935-9
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