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SOX2-dependent expression of dihydroorotate dehydrogenase regulates oral squamous cell carcinoma cell proliferation

Oral squamous cell carcinoma (OSCC) become a heavy burden of public health, with approximately 300 000 newly diagnosed cases and 145 000 deaths worldwide per year. Nucleotide metabolism fuel DNA replication and RNA synthesis, which is indispensable for cell proliferation. But how tumor cells orchest...

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Detalles Bibliográficos
Autores principales:	Qiu, Xuemei, Jiang, Sheng, Xiao, Yanxuan, He, Yumin, Ren, Tao, Jiang, Lu, Liu, Rui, Chen, Qianming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844284/ https://www.ncbi.nlm.nih.gov/pubmed/33510132 http://dx.doi.org/10.1038/s41368-020-00109-x

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