Cargando…

Telomere Dysfunction in Chronic Lymphocytic Leukemia

Telomeres are nucleprotein structures that cap the chromosomal ends, conferring genomic stability. Alterations in telomere maintenance and function are associated with tumorigenesis. In chronic lymphocytic leukemia (CLL), telomere length is an independent prognostic factor and short telomeres are as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jebaraj, Billy Michael Chelliah, Stilgenbauer, Stephan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844343/ https://www.ncbi.nlm.nih.gov/pubmed/33520723 http://dx.doi.org/10.3389/fonc.2020.612665

Ejemplares similares

Integrative prognostic models predict long-term survival after immunochemotherapy in chronic lymphocytic leukemia patients
por: Bloehdorn, Johannes, et al.
Publicado: (2021)

Advances in treating chronic lymphocytic leukemia
por: Tausch, Eugen, et al.
Publicado: (2014)

Refractory chronic lymphocytic leukemia – new therapeutic strategies
por: Schnaiter, Andrea, et al.
Publicado: (2010)

Revolution of Chronic Lymphocytic Leukemia Therapy: the Chemo-Free Treatment Paradigm
por: Scheffold, Annika, et al.
Publicado: (2020)

Telomere shortening leads to an acceleration of synucleinopathy and impaired microglia response in a genetic mouse model
por: Scheffold, Annika, et al.
Publicado: (2016)

Cellular origin and pathophysiology of chronic lymphocytic leukemia
por: Seifert, Marc, et al.
Publicado: (2012)

Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia
por: Bloehdorn, Johannes, et al.
Publicado: (2021)

NOTCH1 Aberrations in Chronic Lymphocytic Leukemia
por: Rosati, Emanuela, et al.
Publicado: (2018)

Measurable residual disease in chronic lymphocytic leukemia
por: Benintende, Giulia, et al.
Publicado: (2023)

DNA methylation of chronic lymphocytic leukemia with differential response to chemotherapy
por: Yosifov, Deyan Yordanov, et al.
Publicado: (2020)

Profile of venetoclax and its potential in the context of treatment of relapsed or refractory chronic lymphocytic leukemia
por: Huber, Henriette, et al.
Publicado: (2017)

Immunotherapeutic Strategies in Chronic Lymphocytic Leukemia: Advances and Challenges
por: Perutelli, Francesca, et al.
Publicado: (2022)

Telomere status in chronic lymphocytic leukemia with TP53 disruption
por: Guièze, Romain, et al.
Publicado: (2016)

Proliferative Signals in Chronic Lymphocytic Leukemia; What Are We Missing?
por: Haselager, Marco V., et al.
Publicado: (2020)

Autoimmune Cytopenias in Chronic Lymphocytic Leukemia: Focus on Molecular Aspects
por: Fattizzo, Bruno, et al.
Publicado: (2020)

CD200 and Chronic Lymphocytic Leukemia: Biological and Clinical Relevance
por: D’Arena, Giovanni, et al.
Publicado: (2020)

Precision diagnostics in chronic lymphocytic leukemia: Past, present and future
por: Mollstedt, John, et al.
Publicado: (2023)

Prognostic and predictive role of gene mutations in chronic lymphocytic leukemia: results from the pivotal phase III study COMPLEMENT1
por: Tausch, Eugen, et al.
Publicado: (2020)

Nucleosome repositioning in chronic lymphocytic leukemia
por: Piroeva, Kristan V., et al.
Publicado: (2023)

Role of NFAT in Chronic Lymphocytic Leukemia and Other B-Cell Malignancies
por: Sana, Ilenia, et al.
Publicado: (2021)

Treatment Approaches to Chronic Lymphocytic Leukemia With High-Risk Molecular Features
por: van der Straten, Lina, et al.
Publicado: (2021)

Chromothripsis in Chronic Lymphocytic Leukemia: A Driving Force of Genome Instability
por: Zavacka, Kristyna, et al.
Publicado: (2021)

Altered T Follicular Helper Cell Subsets and Function in Chronic Lymphocytic Leukemia
por: Wu, Xun, et al.
Publicado: (2021)

AID in Chronic Lymphocytic Leukemia: Induction and Action During Disease Progression
por: Oppezzo, Pablo, et al.
Publicado: (2021)

Minimal Residual Disease in Chronic Lymphocytic Leukemia: A New Goal?
por: Del Giudice, Ilaria, et al.
Publicado: (2019)

Current state of NK cell-mediated immunotherapy in chronic lymphocytic leukemia
por: Wang, Zong-Han, et al.
Publicado: (2023)

Paradoxical activation of chronic lymphocytic leukemia cells by ruxolitinib in vitro and in vivo
por: Spaner, David E., et al.
Publicado: (2023)

Synchronous or Metachronous Hairy Cell Leukemia and Chronic Lymphocytic Leukemia: A Case Series and Literature Review
por: Verma, Vivek, et al.
Publicado: (2017)

TP53 aberrations in chronic lymphocytic leukemia: an overview of the clinical implications of improved diagnostics
por: Campo, Elias, et al.
Publicado: (2018)

Clonal Evolution of High-Risk Chronic Lymphocytic Leukemia: A Contemporary Perspective
por: Kwok, Marwan, et al.
Publicado: (2021)

NOTCH1 Is Aberrantly Activated in Chronic Lymphocytic Leukemia Hematopoietic Stem Cells
por: Di Ianni, Mauro, et al.
Publicado: (2018)

Time to Treatment Prediction in Chronic Lymphocytic Leukemia Based on New Transcriptional Patterns
por: Mosquera Orgueira, Adrián, et al.
Publicado: (2019)

Resistance-Associated Mutations in Chronic Lymphocytic Leukemia Patients Treated With Novel Agents
por: Sedlarikova, Lenka, et al.
Publicado: (2020)

“Double-Hit” Chronic Lymphocytic Leukemia, Involving the TP53 and MYC Genes
por: Nguyen-Khac, Florence
Publicado: (2022)

The role of allogeneic hematopoietic cell transplantation for chronic lymphocytic leukemia: A review
por: Puckrin, Robert, et al.
Publicado: (2023)

The evolving use of measurable residual disease in chronic lymphocytic leukemia clinical trials
por: Fisher, A., et al.
Publicado: (2023)

Germline Allele-Specific Expression of DAPK1 in Chronic Lymphocytic Leukemia
por: Wei, Quan-Xiang, et al.
Publicado: (2013)

Acquired BTK mutations associated with resistance to noncovalent BTK inhibitors
por: Qi, Jialei, et al.
Publicado: (2023)

P614: NOVEL SPLICE-SITE MUTATION IN PLCG2 ASSOCIATED WITH RESISTANCE TO BTK INHIBITORS
por: Qi, Jialei, et al.
Publicado: (2023)

Case report: Hematologic malignancies concomitant diagnosis of hairy cell leukemia and chronic lymphocytic leukemia: A rare association
por: Valvano, Luciana, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_93os4ef3en7f3hj21ekusplj1g