Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver

Hepatocellular carcinoma (HCC) is the most predominant primary malignancy in the liver. Genotoxic and genetic models have revealed that HCC cells are derived from hepatocytes, but where the critical region for tumor foci emergence is and how this transformation occurs are still unclear. Here, hyperp...

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Detalles Bibliográficos
Autores principales: Lin, Heng, Huang, Yen-Sung, Fustin, Jean-Michel, Doi, Masao, Chen, Huatao, Lai, Hui-Huang, Lin, Shu-Hui, Lee, Yen-Lurk, King, Pei-Chih, Hou, Hsien-San, Chen, Hao-Wen, Young, Pei-Yun, Chao, Hsu-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844417/
https://www.ncbi.nlm.nih.gov/pubmed/33510150
http://dx.doi.org/10.1038/s41467-020-20572-8

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