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ANO5 ensures trafficking of annexins in wounded myofibers

Mutations in ANO5 (TMEM16E) cause limb-girdle muscular dystrophy R12. Defective plasma membrane repair is a likely mechanism. Using myofibers from Ano5 knockout mice, we show that trafficking of several annexin proteins, which together form a cap at the site of injury, is altered upon loss of ANO5....

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Detalles Bibliográficos
Autores principales: Foltz, Steven J., Cui, Yuan Yuan, Choo, Hyojung J., Hartzell, H. Criss
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844426/
https://www.ncbi.nlm.nih.gov/pubmed/33496727
http://dx.doi.org/10.1083/jcb.202007059

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