Biochemical reconstitutions reveal principles of human γ-TuRC assembly and function

The formation of cellular microtubule networks is regulated by the γ-tubulin ring complex (γ-TuRC). This ∼2.3 MD assembly of >31 proteins includes γ-tubulin and GCP2-6, as well as MZT1 and an actin-like protein in a “lumenal bridge” (LB). The challenge of reconstituting the γ-TuRC has limited dis...

Descripción completa

Detalles Bibliográficos
Autores principales: Wieczorek, Michal, Ti, Shih-Chieh, Urnavicius, Linas, Molloy, Kelly R., Aher, Amol, Chait, Brian T., Kapoor, Tarun M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844428/
https://www.ncbi.nlm.nih.gov/pubmed/33496729
http://dx.doi.org/10.1083/jcb.202009146

Ejemplares similares

Ejemplares similares