Cargando…

Signal Recognition Particle Suppressor Screening Reveals the Regulation of Membrane Protein Targeting by the Translation Rate

The signal recognition particle (SRP) is conserved in all living organisms, and it cotranslationally delivers proteins to the inner membrane or endoplasmic reticulum. Recently, SRP loss was found not to be lethal in either the eukaryote Saccharomyces cerevisiae or the prokaryote Streptococcus mutans...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Liuqun, Cui, Yanyan, Fu, Gang, Xu, Zixiang, Liao, Xiaoping, Zhang, Dawei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844537/ https://www.ncbi.nlm.nih.gov/pubmed/33436432 http://dx.doi.org/10.1128/mBio.02373-20

Ejemplares similares

Compensating Complete Loss of Signal Recognition Particle During Co-translational Protein Targeting by the Translation Speed and Accuracy
por: Zhao, Liuqun, et al.
Publicado: (2021)

Multimer recognition and secretion by the non-classical secretion pathway in Bacillus subtilis
por: Zhao, Liuqun, et al.
Publicado: (2017)

A novel strategy for protein production using non-classical secretion pathway in Bacillus subtilis
por: Chen, Jingqi, et al.
Publicado: (2016)

Real-time observation of signal recognition particle binding to actively translating ribosomes
por: Noriega, Thomas R, et al.
Publicado: (2014)

Cohesin organization, dynamics, and subdomain functions revealed by genetic suppressor screening
por: XU, Xingya, et al.
Publicado: (2023)

Posttranslational insertion of small membrane proteins by the bacterial signal recognition particle
por: Steinberg, Ruth, et al.
Publicado: (2020)

Multicopy suppressor screens reveal convergent evolution of single-gene lysis proteins
por: Adler, Benjamin A., et al.
Publicado: (2023)

Signal recognition particle binds to translating ribosomes before emergence of a signal anchor sequence
por: Mercier, Evan, et al.
Publicado: (2017)

Identification of lysine-lactylated substrates in gastric cancer cells
por: Yang, Dawei, et al.
Publicado: (2022)

Predominant membrane localization is an essential feature of the bacterial signal recognition particle receptor
por: Mircheva, Miryana, et al.
Publicado: (2009)

Signal recognition particle prevents N-terminal processing of bacterial membrane proteins
por: Ranjan, Amitabh, et al.
Publicado: (2017)

Regulating tumor suppressor genes: post-translational modifications
por: Chen, Ling, et al.
Publicado: (2020)

Protein synthesis rates and ribosome occupancies reveal determinants of translation elongation rates
por: Riba, Andrea, et al.
Publicado: (2019)

SRPassing Co-translational Targeting: The Role of the Signal Recognition Particle in Protein Targeting and mRNA Protection
por: Kellogg, Morgana K., et al.
Publicado: (2021)

Accumulation of endoplasmic membranes and novel membrane-bound ribosome–signal recognition particle receptor complexes in Escherichia coli
por: Herskovits, Anat A., et al.
Publicado: (2002)

GTP hydrolysis by complexes of the signal recognition particle and the signal recognition particle receptor
Publicado: (1993)

Signal recognition particle-dependent insertion of coronavirus E1, an intracellular membrane glycoprotein.
por: Rottier, P, et al.
Publicado: (1985)

Regulation of the tumor suppressor PML by sequential post-translational modifications
por: Schmitz, M. Lienhard, et al.
Publicado: (2012)

Uncovering the Translational Regulatory Activity of the Tumor Suppressor BRCA1
por: Berthel, Elise, et al.
Publicado: (2020)

Dictating translations with automatic speech recognition: Effects on translators’ performance
por: Wang, Lulu, et al.
Publicado: (2023)

A Genomewide Screen for Suppressors of Alu-Mediated Rearrangements Reveals a Role for PIF1
por: Chisholm, Karen M., et al.
Publicado: (2012)

Suppressor screening reveals common kleisin–hinge interaction in condensin and cohesin, but different modes of regulation
por: Xu, Xingya, et al.
Publicado: (2019)

Unidirectional constant rate motion of the ribosomal scanning particle during eukaryotic translation initiation
por: Vassilenko, Konstantin S., et al.
Publicado: (2011)

p53 Isoforms as Cancer Biomarkers and Therapeutic Targets
por: Zhao, Liuqun, et al.
Publicado: (2022)

Recognition of a signal peptide by the signal recognition particle
por: Janda, Claudia Y., et al.
Publicado: (2010)

Myeloid-derived suppressor cell: A crucial player in autoimmune diseases
por: Xu, Dandan, et al.
Publicado: (2022)

Membrane binding of the bacterial signal recognition particle receptor involves two distinct binding sites
por: Angelini, Sandra, et al.
Publicado: (2006)

Structural Basis for ASPP2 Recognition by the Tumor Suppressor p73
por: Canning, Peter, et al.
Publicado: (2012)

Myeloid-derived suppressor cells: key immunosuppressive regulators and therapeutic targets in hematological malignancies
por: Wang, Shifen, et al.
Publicado: (2023)

Evolution and Targeting of Myeloid Suppressor Cells in Cancer: A Translational Perspective
por: Bleve, Augusto, et al.
Publicado: (2022)

X-ray Structures of the Signal Recognition Particle Receptor Reveal Targeting Cycle Intermediates
por: Reyes, Christopher L., et al.
Publicado: (2007)

In vivo screen for suppressors of long QT syndrome
Publicado: (2011)

Effects of Membrane Structure on Oil–Water Separation by Smoothed Particle Hydrodynamics
por: Liu, Jie, et al.
Publicado: (2022)

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors
por: Feng, Xu, et al.
Publicado: (2022)

Heme oxygenase-independent bilin biosynthesis revealed by a hmox1 suppressor screening in Chlamydomonas reinhardtii
por: Zhang, Weiqing, et al.
Publicado: (2022)

cccDNA-Targeted Drug Screen Reveals a Class of Antihistamines as Suppressors of HBV Genome Levels
por: Ren, Ee Chee, et al.
Publicado: (2023)

Tumor suppressor p53 protects mice against Listeria monocytogenes infection
por: Wang, Shaohui, et al.
Publicado: (2016)

Intragenic Suppressor of Osiaa23 Revealed a Conserved Tryptophan Residue Crucial for Protein-Protein Interactions
por: Ni, Jun, et al.
Publicado: (2014)

circPSMC3: ceRNA and tumor suppressor
por: Lu, Chen, et al.
Publicado: (2019)

Structures of the Signal Recognition Particle Receptor from the Archaeon Pyrococcus furiosus: Implications for the Targeting Step at the Membrane
por: Egea, Pascal F., et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_sv87nnt666502dnj3gi8rm6eto