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Structural basis of enzyme activity regulation by the propeptide of l-lysine α-oxidase precursor from Trichoderma viride
Harmuful proteins are usually synthesized as inactive precursors and are activated by proteolytic processing. l-Amino acid oxidase (LAAO) is a flavoenzyme that catalyzes the oxidative deamination of l-amino acid to produce a 2-oxo acid with ammonia and highly toxic hydrogen peroxide and, therefore,...
Autores principales: | Kitagawa, Masaki, Ito, Nanako, Matsumoto, Yuya, Saito, Masaya, Tamura, Takashi, Kusakabe, Hitoshi, Inagaki, Kenji, Imada, Katsumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844570/ https://www.ncbi.nlm.nih.gov/pubmed/33554108 http://dx.doi.org/10.1016/j.yjsbx.2021.100044 |
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