Cargando…

Corilagin Induces High Levels of Apoptosis in the Temozolomide-Resistant T98G Glioma Cell Line

Glioblastoma multiforme (GBM), a malignant tumor of the central nervous system, has a high mortality rate. No curative treatment is presently available, and the most commonly used chemotherapeutic drug, the alkylating agent temozolomide (TMZ), is only able to increase life expectancy and is often as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Milani, Roberta, Brognara, Eleonora, Fabbri, Enrica, Finotti, Alessia, Borgatti, Monica, Lampronti, Ilaria, Marzaro, Giovanni, Chilin, Adriana, Lee, Kenneth Ka-Ho, Kok, Stanton Hon-Lung, Chui, Chung-Hin, Gambari, Roberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cognizant Communication Corporation 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844640/ https://www.ncbi.nlm.nih.gov/pubmed/28474573 http://dx.doi.org/10.3727/096504017X14928634401187

Ejemplares similares

Targeting miR-155-5p and miR-221-3p by peptide nucleic acids induces caspase-3 activation and apoptosis in temozolomide-resistant T98G glioma cells
por: Milani, Roberta, et al.
Publicado: (2019)

The Loss of Cellular Junctions in Epithelial Lung Cells Induced by Cigarette Smoke Is Attenuated by Corilagin
por: Muresan, Ximena M., et al.
Publicado: (2015)

Increase of microRNA-210, Decrease of Raptor Gene Expression and Alteration of Mammalian Target of Rapamycin Regulated Proteins following Mithramycin Treatment of Human Erythroid Cells
por: Bianchi, Nicoletta, et al.
Publicado: (2015)

MicroRNAs and Long Non-coding RNAs in Genetic Diseases
por: Finotti, Alessia, et al.
Publicado: (2019)

Differential Effects of Angelicin Analogues on NF-κB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells
por: Lampronti, Ilaria, et al.
Publicado: (2017)

Role of Cystic Fibrosis Bronchial Epithelium in Neutrophil Chemotaxis
por: Cabrini, Giulio, et al.
Publicado: (2020)

Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions
por: Finotti, Alessia, et al.
Publicado: (2015)

A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs
por: Prosdocimi, Marco, et al.
Publicado: (2022)

Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: New trends in the development of miRNA therapeutic strategies in oncology (Review)
por: GAMBARI, ROBERTO, et al.
Publicado: (2016)

BCL11A mRNA Targeting by miR-210: A Possible Network Regulating γ-Globin Gene Expression
por: Gasparello, Jessica, et al.
Publicado: (2017)

A Peptide-Nucleic Acid Targeting miR-335-5p Enhances Expression of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene with the Possible Involvement of the CFTR Scaffolding Protein NHERF1
por: Tamanini, Anna, et al.
Publicado: (2021)

UPF1 silenced cellular model systems for screening of read-through agents active on β(0)39 thalassemia point mutation
por: Salvatori, Francesca, et al.
Publicado: (2018)

Treatment of Erythroid Precursor Cells from β-Thalassemia Patients with Cinchona Alkaloids: Induction of Fetal Hemoglobin Production
por: Zuccato, Cristina, et al.
Publicado: (2021)

Regulation of IL-8 gene expression in gliomas by microRNA miR-93
por: Fabbri, Enrica, et al.
Publicado: (2015)

Pro-apoptotic activity of novel synthetic isoxazole derivatives exhibiting inhibitory activity against tumor cell growth in vitro
por: Lampronti, Ilaria, et al.
Publicado: (2020)

Differential effects on the miRNome of the treatment of human airway epithelial Calu-3 cells with peptide-nucleic acids (PNAs) targeting microRNAs miR-101-3p and miR-145-5p: Next generation sequencing datasets
por: Gasparello, Jessica, et al.
Publicado: (2021)

A Peptide Nucleic Acid against MicroRNA miR-145-5p Enhances the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Calu-3 Cells
por: Fabbri, Enrica, et al.
Publicado: (2017)

Induction of erythroid differentiation and increased globin mRNA production with furocoumarins and their photoproducts
por: Salvador, Alessia, et al.
Publicado: (2013)

Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells
por: MONTAGNER, GIULIA, et al.
Publicado: (2015)

C(5) modified uracil derivatives showing antiproliferative and erythroid differentiation inducing activities on human chronic myelogenous leukemia K562 cells
por: Brognara, Eleonora, et al.
Publicado: (2011)

A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction
por: Zuccato, Cristina, et al.
Publicado: (2012)

Molecular Mechanism of Action of Trimethylangelicin Derivatives as CFTR Modulators
por: Laselva, Onofrio, et al.
Publicado: (2018)

The rs368698783 (G>A) Polymorphism Affecting LYAR Binding to the Aγ-Globin Gene Is Associated with High Fetal Hemoglobin (HbF) in β-Thalassemia Erythroid Precursor Cells Treated with HbF Inducers
por: Zuccato, Cristina, et al.
Publicado: (2023)

Effects of decoy molecules targeting NF-kappaB transcription factors in Cystic fibrosis IB3–1 cells: Recruitment of NF-kappaB to the IL-8 gene promoter and transcription of the IL-8 gene
por: Finotti, Alessia, et al.
Publicado: (2012)

An Aγ-globin G->A gene polymorphism associated with β(0)39 thalassemia globin gene and high fetal hemoglobin production
por: Breveglieri, Giulia, et al.
Publicado: (2017)

A Peptide Nucleic Acid (PNA) Masking the miR-145-5p Binding Site of the 3′UTR of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) mRNA Enhances CFTR Expression in Calu-3 Cells
por: Sultan, Shaiq, et al.
Publicado: (2020)

Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression
por: Piccagli, Laura, et al.
Publicado: (2008)

Fetal Hemoglobin Inducers from the Natural World: A Novel Approach for Identification of Drugs for the Treatment of β-Thalassemia and Sickle-Cell Anemia
por: Bianchi, Nicoletta, et al.
Publicado: (2009)

Modulation of the Expression of the Proinflammatory IL-8 Gene in Cystic Fibrosis Cells by Extracts Deriving from Olive Mill Waste Water
por: Lampronti, Ilaria, et al.
Publicado: (2013)

Targeting pre-miRNA by Peptide Nucleic Acids: A new strategy to interfere in the miRNA maturation
por: Avitabile, Concetta, et al.
Publicado: (2012)

Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia
por: Capretto, Lorenzo, et al.
Publicado: (2012)

Liquid biopsy in mice bearing colorectal carcinoma xenografts: gateways regulating the levels of circulating tumor DNA (ctDNA) and miRNA (ctmiRNA)
por: Gasparello, Jessica, et al.
Publicado: (2018)

Sulforaphane inhibits the expression of interleukin-6 and interleukin-8 induced in bronchial epithelial IB3-1 cells by exposure to the SARS-CoV-2 Spike protein
por: Gasparello, Jessica, et al.
Publicado: (2021)

trans-Resveratrol in Nutraceuticals: Issues in Retail Quality and Effectiveness
por: Rossi, Damiano, et al.
Publicado: (2012)

In vitro induction of interleukin-8 by SARS-CoV-2 Spike protein is inhibited in bronchial epithelial IB3-1 cells by a miR-93-5p agomiR
por: Gasparello, Jessica, et al.
Publicado: (2021)

Synergistic effects of the combined treatment of U251 and T98G glioma cells with an anti-tubulin tetrahydrothieno[2,3-c]pyridine derivative and a peptide nucleic acid targeting miR-221-3p
por: Zurlo, Matteo, et al.
Publicado: (2021)

Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β-Globin Gene with the IVSI-6 Thalassemia Mutation
por: Breveglieri, Giulia, et al.
Publicado: (2015)

Effects of Sulforaphane on SARS-CoV-2 infection and NF-κB dependent expression of genes involved in the COVID-19 'cytokine storm'
por: Gasparello, Jessica, et al.
Publicado: (2023)

Cellular Uptakes, Biostabilities and Anti-miR-210 Activities of Chiral Arginine-PNAs in Leukaemic K562 Cells
por: Manicardi, Alex, et al.
Publicado: (2012)

Effects of Mithramycin on BCL11A Gene Expression and on the Interaction of the BCL11A Transcriptional Complex to γ-Globin Gene Promoter Sequences
por: Finotti, Alessia, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_02bkbl4cj1nlhc55glr0du21p7