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Tanshinone Suppresses Arecoline-Induced Epithelial–Mesenchymal Transition in Oral Submucous Fibrosis by Epigenetically Reactivating the p53 Pathway

Oral submucous fibrosis (OSF) induced by chewing of the areca nut has been considered to be a precancerous lesion with a high probability of developing oral squamous cell carcinoma. Tanshinone (TSN) is the main component extracted from Salvia miltiorrhiza, a traditional Chinese medicine, which was f...

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Detalles Bibliográficos
Autores principales:	Zheng, Lian, Guan, Zhen-Jie, Pan, Wen-Ting, Du, Tian-Feng, Zhai, Yu-Jia, Guo, Jia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cognizant Communication Corporation 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844836/ https://www.ncbi.nlm.nih.gov/pubmed/28550687 http://dx.doi.org/10.3727/096504017X14941825760362

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