Aspergillus fumigatus tryptophan metabolic route differently affects host immunity

Indoleamine 2,3-dioxygenases (IDOs) degrade l-tryptophan to kynurenines and drive the de novo synthesis of nicotinamide adenine dinucleotide. Unsurprisingly, various invertebrates, vertebrates, and even fungi produce IDO. In mammals, IDO1 also serves as a homeostatic regulator, modulating immune res...

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Detalles Bibliográficos
Autores principales: Zelante, Teresa, Choera, Tsokyi, Beauvais, Anne, Fallarino, Francesca, Paolicelli, Giuseppe, Pieraccini, Giuseppe, Pieroni, Marco, Galosi, Claudia, Beato, Claudia, De Luca, Antonella, Boscaro, Francesca, Romoli, Riccardo, Liu, Xin, Warris, Adilia, Verweij, Paul E., Ballard, Eloise, Borghi, Monica, Pariano, Marilena, Costantino, Gabriele, Calvitti, Mario, Vacca, Carmine, Oikonomou, Vasilis, Gargaro, Marco, Wong, Alicia Yoke Wei, Boon, Louis, den Hartog, Marcel, Spáčil, Zdeněk, Puccetti, Paolo, Latgè, Jean-Paul, Keller, Nancy P., Romani, Luigina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844877/
https://www.ncbi.nlm.nih.gov/pubmed/33503414
http://dx.doi.org/10.1016/j.celrep.2020.108673

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