Generation of dyskeratosis congenita-like hematopoietic stem cells through the stable inhibition of DKC1

Dyskeratosis congenita (DC) is a rare telomere biology disorder, which results in different clinical manifestations, including severe bone marrow failure. To date, the only curative treatment for the bone marrow failure in DC patients is allogeneic hematopoietic stem cell transplantation. However, d...

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Detalles Bibliográficos
Autores principales: Carrascoso-Rubio, Carlos, Zittersteijn, Hidde A., Pintado-Berninches, Laura, Fernández-Varas, Beatriz, Lozano, M. Luz, Manguan-Garcia, Cristina, Sastre, Leandro, Bueren, Juan A., Perona, Rosario, Guenechea, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844988/
https://www.ncbi.nlm.nih.gov/pubmed/33514435
http://dx.doi.org/10.1186/s13287-021-02145-8

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