Neutrophil extracellular trap regulators in sickle cell disease: Modulation of gene expression of PADI4, neutrophil elastase, and myeloperoxidase during vaso‐occlusive crisis

BACKGROUND: Recent evidence suggests that generation of neutrophil extracellular traps (NETosis), one of the components of immunothrombosis, is associated with the pathogenesis of both venous thromboembolism and sickle cell disease (SCD). NETosis is a complex process regulated by several proteins su...

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Detalles Bibliográficos
Autores principales: Hounkpe, Bidossessi Wilfried, Chenou, Francine, Domingos, Igor de Farias, Cardoso, Evilazio Cunha, Costa Sobreira, Marcondes José de Vasconcelos, Araujo, Aderson S., Lucena‐Araújo, Antonio Roberto, da Silva Neto, Pedro Vieira, Malheiro, Adriana, Fraiji, Nelson Abrahim, Costa, Fernando Ferreira, Bezerra, Marcos André C., Santos, Magnun Nueldo Nunes, De Paula, Erich Vinicius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles ‐ Thrombosis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845058/
https://www.ncbi.nlm.nih.gov/pubmed/33537545
http://dx.doi.org/10.1002/rth2.12463

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