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Complement factor C4a does not activate protease‐activated receptor 1 (PAR1) or PAR4 on human platelets

BACKGROUND: Protease‐activated receptor (PAR) 1 and PAR4 are key thrombin signal mediators for human platelet activation and aggregation in response to vascular injury. They are primarily activated by thrombin cleavage of the N‐terminus to expose a tethered ligand. In addition to the canonical activ...

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Detalles Bibliográficos
Autores principales:	Han, Xu, de la Fuente, Maria, Nieman, Marvin T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles ‐ Hemostasis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845074/ https://www.ncbi.nlm.nih.gov/pubmed/33537534 http://dx.doi.org/10.1002/rth2.12459

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