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Highly elevated polygenic risk scores are better predictors of myocardial infarction risk early in life than later

BACKGROUND: Several polygenic risk scores (PRS) have been developed for cardiovascular risk prediction, but the additive value of including PRS together with conventional risk factors for risk prediction is questionable. This study assesses the clinical utility of including four PRS generated from 1...

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Detalles Bibliográficos
Autores principales:	Isgut, Monica, Sun, Jimeng, Quyyumi, Arshed A., Gibson, Greg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845089/ https://www.ncbi.nlm.nih.gov/pubmed/33509272 http://dx.doi.org/10.1186/s13073-021-00828-8

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