Prion-induced photoreceptor degeneration begins with misfolded prion protein accumulation in cones at two distinct sites: cilia and ribbon synapses

Accumulation of misfolded host proteins is central to neuropathogenesis of numerous human brain diseases including prion and prion-like diseases. Neurons of retina are also affected by these diseases. Previously, our group and others found that prion-induced retinal damage to photoreceptor cells in...

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Detalles Bibliográficos
Autores principales: Striebel, James F., Race, Brent, Leung, Jacqueline M., Schwartz, Cindi, Chesebro, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845122/
https://www.ncbi.nlm.nih.gov/pubmed/33509294
http://dx.doi.org/10.1186/s40478-021-01120-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845122/
https://www.ncbi.nlm.nih.gov/pubmed/33509294
http://dx.doi.org/10.1186/s40478-021-01120-x

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