β-Lapachone ameliorates L-DOPA-induced dyskinesia in a 6-OHDA-induced mouse model of Parkinson's disease

The dopamine precursor 3,4-dihydroxyphenyl- l-alanine (L-DOPA) is the most widely used symptomatic treatment for Parkinson's disease (PD); however, its prolonged use is associated with L-DOPA-induced dyskinesia in more than half of patients after 10 years of treatment. The present study investi...

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Autores principales: Ryu, Young-Kyoung, Park, Hye-Yeon, Go, Jun, Lee, In-Bok, Choi, Young-Keun, Lee, Chul-Ho, Kim, Kyoung-Shim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845622/
https://www.ncbi.nlm.nih.gov/pubmed/33495840
http://dx.doi.org/10.3892/mmr.2021.11856

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