Engineering a Reliable and Convenient SARS-CoV-2 Replicon System for Analysis of Viral RNA Synthesis and Screening of Antiviral Inhibitors

The etiologic agent of COVID-19 is highly contagious and has caused a severe global pandemic. Until now, there has been no simple and reliable system available in a lower-biosafety-grade laboratory for SARS-CoV-2 virologic research and inhibitor screening. In this study, we reported a replicon syste...

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Detalles Bibliográficos
Autores principales: Luo, Yuewen, Yu, Fei, Zhou, Mo, Liu, Yang, Xia, Baijin, Zhang, Xiantao, Liu, Jun, Zhang, Junsong, Du, Yingying, Li, Rong, Wu, Liyang, Zhang, Xu, Pan, Ting, Guo, Deyin, Peng, Tao, Zhang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845634/
https://www.ncbi.nlm.nih.gov/pubmed/33468688
http://dx.doi.org/10.1128/mBio.02754-20

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