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Sterilization by Adaptive Immunity of a Conditionally Persistent Mutant of Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, can enter into a persistent state that confers resistance to antibacterial agents. Many observations suggest that persistent M. tuberculosis cells also evade the antimycobacterial immune mechanisms, thereby reducing the effective...

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Detalles Bibliográficos
Autores principales: Vilchèze, Catherine, Porcelli, Steven A., Chan, John, Jacobs, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845640/
https://www.ncbi.nlm.nih.gov/pubmed/33468684
http://dx.doi.org/10.1128/mBio.02391-20