Stenoparib, an Inhibitor of Cellular Poly(ADP-Ribose) Polymerase, Blocks Replication of the SARS-CoV-2 and HCoV-NL63 Human Coronaviruses In Vitro

By late 2020, the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), had caused tens of millions of infections and over 1 million deaths worldwide. A protective vaccine and more effective therapeutics are urgently needed. We evaluate...

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Detalles Bibliográficos
Autores principales: Stone, Nathan E., Jaramillo, Sierra A., Jones, Ashley N., Vazquez, Adam J., Martz, Madison, Versluis, Lora M., Raniere, Marlee O., Nunnally, Haley E., Zarn, Katherine E., Nottingham, Roxanne, Ng, Ken R., Sahl, Jason W., Wagner, David M., Knudsen, Steen, Settles, Erik W., Keim, Paul, French, Christopher T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845641/
https://www.ncbi.nlm.nih.gov/pubmed/33468703
http://dx.doi.org/10.1128/mBio.03495-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845641/
https://www.ncbi.nlm.nih.gov/pubmed/33468703
http://dx.doi.org/10.1128/mBio.03495-20

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