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Stenoparib, an Inhibitor of Cellular Poly(ADP-Ribose) Polymerase, Blocks Replication of the SARS-CoV-2 and HCoV-NL63 Human Coronaviruses In Vitro
By late 2020, the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), had caused tens of millions of infections and over 1 million deaths worldwide. A protective vaccine and more effective therapeutics are urgently needed. We evaluate...
Autores principales: | Stone, Nathan E., Jaramillo, Sierra A., Jones, Ashley N., Vazquez, Adam J., Martz, Madison, Versluis, Lora M., Raniere, Marlee O., Nunnally, Haley E., Zarn, Katherine E., Nottingham, Roxanne, Ng, Ken R., Sahl, Jason W., Wagner, David M., Knudsen, Steen, Settles, Erik W., Keim, Paul, French, Christopher T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845641/ https://www.ncbi.nlm.nih.gov/pubmed/33468703 http://dx.doi.org/10.1128/mBio.03495-20 |
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