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Exploring the Impact of Ketodeoxynonulosonic Acid in Host-Pathogen Interactions Using Uptake and Surface Display by Nontypeable Haemophilus influenzae
Surface expression of the common vertebrate sialic acid (Sia) N-acetylneuraminic acid (Neu5Ac) by commensal and pathogenic microbes appears structurally to represent “molecular mimicry” of host sialoglycans, facilitating multiple mechanisms of host immune evasion. In contrast, ketodeoxynonulosonic a...
Autores principales: | Saha, Sudeshna, Coady, Alison, Sasmal, Aniruddha, Kawanishi, Kunio, Choudhury, Biswa, Yu, Hai, Sorensen, Ricardo U., Inostroza, Jaime, Schoenhofen, Ian C., Chen, Xi, Münster-Kühnel, Anja, Sato, Chihiro, Kitajima, Ken, Ram, Sanjay, Nizet, Victor, Varki, Ajit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845648/ https://www.ncbi.nlm.nih.gov/pubmed/33468699 http://dx.doi.org/10.1128/mBio.03226-20 |
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