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Bilateral ocular toxoplasmosis in a returning traveller: age and route of infection as potential risk factors

We report the case of a 69-year-old man, who presented in the UK with a short history of deteriorating vision and clinical features of bilateral atypical retinochoroiditis, after travelling to South America. Vitreous samples demonstrated Toxoplasma gondii DNA by PCR. Serology tests demonstrated rece...

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Detalles Bibliográficos
Autores principales: Seers, Tim, Myneni, Jayavani, Chaudhry, Nadia L, Ugarte, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845719/
https://www.ncbi.nlm.nih.gov/pubmed/33509864
http://dx.doi.org/10.1136/bcr-2020-237068
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author Seers, Tim
Myneni, Jayavani
Chaudhry, Nadia L
Ugarte, Marta
author_facet Seers, Tim
Myneni, Jayavani
Chaudhry, Nadia L
Ugarte, Marta
author_sort Seers, Tim
collection PubMed
description We report the case of a 69-year-old man, who presented in the UK with a short history of deteriorating vision and clinical features of bilateral atypical retinochoroiditis, after travelling to South America. Vitreous samples demonstrated Toxoplasma gondii DNA by PCR. Serology tests demonstrated recent acquired Toxoplasma gondii infection with IgM antibodies. He responded well to treatment with trimethoprim-sulfamethoxazole, azithromycin and oral steroids. This case is a reminder of the global importance of Toxoplasma related eye disease, and its uncommon bilateral severe presentation in a returning traveller, where the risk factors were age and the route of infection likely to be a virulent parasite oocyst from vegetables or water rather than undercooked meat or direct contact with cats.
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spelling pubmed-78457192021-02-04 Bilateral ocular toxoplasmosis in a returning traveller: age and route of infection as potential risk factors Seers, Tim Myneni, Jayavani Chaudhry, Nadia L Ugarte, Marta BMJ Case Rep Case Report We report the case of a 69-year-old man, who presented in the UK with a short history of deteriorating vision and clinical features of bilateral atypical retinochoroiditis, after travelling to South America. Vitreous samples demonstrated Toxoplasma gondii DNA by PCR. Serology tests demonstrated recent acquired Toxoplasma gondii infection with IgM antibodies. He responded well to treatment with trimethoprim-sulfamethoxazole, azithromycin and oral steroids. This case is a reminder of the global importance of Toxoplasma related eye disease, and its uncommon bilateral severe presentation in a returning traveller, where the risk factors were age and the route of infection likely to be a virulent parasite oocyst from vegetables or water rather than undercooked meat or direct contact with cats. BMJ Publishing Group 2021-01-28 /pmc/articles/PMC7845719/ /pubmed/33509864 http://dx.doi.org/10.1136/bcr-2020-237068 Text en © BMJ Publishing Group Limited 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Case Report
Seers, Tim
Myneni, Jayavani
Chaudhry, Nadia L
Ugarte, Marta
Bilateral ocular toxoplasmosis in a returning traveller: age and route of infection as potential risk factors
title Bilateral ocular toxoplasmosis in a returning traveller: age and route of infection as potential risk factors
title_full Bilateral ocular toxoplasmosis in a returning traveller: age and route of infection as potential risk factors
title_fullStr Bilateral ocular toxoplasmosis in a returning traveller: age and route of infection as potential risk factors
title_full_unstemmed Bilateral ocular toxoplasmosis in a returning traveller: age and route of infection as potential risk factors
title_short Bilateral ocular toxoplasmosis in a returning traveller: age and route of infection as potential risk factors
title_sort bilateral ocular toxoplasmosis in a returning traveller: age and route of infection as potential risk factors
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845719/
https://www.ncbi.nlm.nih.gov/pubmed/33509864
http://dx.doi.org/10.1136/bcr-2020-237068
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