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High-fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate
Liquid–liquid phase separation (LLPS) is a mechanism of intracellular organization that underlies the assembly of a variety of RNP granules. Fundamental biophysical principles governing LLPS during granule assembly have been revealed by simple in vitro systems, but these systems have limitations whe...
Autores principales: | Freibaum, Brian D., Messing, James, Yang, Peiguo, Kim, Hong Joo, Taylor, J. Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845923/ https://www.ncbi.nlm.nih.gov/pubmed/33502444 http://dx.doi.org/10.1083/jcb.202009079 |
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