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High-fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate

Liquid–liquid phase separation (LLPS) is a mechanism of intracellular organization that underlies the assembly of a variety of RNP granules. Fundamental biophysical principles governing LLPS during granule assembly have been revealed by simple in vitro systems, but these systems have limitations whe...

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Detalles Bibliográficos
Autores principales: Freibaum, Brian D., Messing, James, Yang, Peiguo, Kim, Hong Joo, Taylor, J. Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845923/
https://www.ncbi.nlm.nih.gov/pubmed/33502444
http://dx.doi.org/10.1083/jcb.202009079

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