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Htt is a repressor of Abl activity required for APP-induced axonal growth

Huntington’s disease is a progressive autosomal dominant neurodegenerative disorder caused by the expansion of a polyglutamine tract at the N-terminus of a large cytoplasmic protein. The Drosophila huntingtin (htt) gene is widely expressed during all developmental stages from embryos to adults. Howe...

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Detalles Bibliográficos
Autores principales:	Marquilly, Claire, Busto, Germain U., Leger, Brittany S., Boulanger, Ana, Giniger, Edward, Walker, James A., Fradkin, Lee G., Dura, Jean-Maurice
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845969/ https://www.ncbi.nlm.nih.gov/pubmed/33465062 http://dx.doi.org/10.1371/journal.pgen.1009287

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