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Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART

The precise role of CD4 T cell turnover in maintaining HIV persistence during antiretroviral therapy (ART) has not yet been well characterized. In resting CD4 T cell subpopulations from 24 HIV-infected ART-suppressed and 6 HIV-uninfected individuals, we directly measured cellular turnover by heavy w...

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Detalles Bibliográficos
Autores principales:	Bacchus-Souffan, Charline, Fitch, Mark, Symons, Jori, Abdel-Mohsen, Mohamed, Reeves, Daniel B., Hoh, Rebecca, Stone, Mars, Hiatt, Joseph, Kim, Peggy, Chopra, Abha, Ahn, Haelee, York, Vanessa A., Cameron, Daniel L., Hecht, Frederick M., Martin, Jeffrey N., Yukl, Steven A., Mallal, Simon, Cameron, Paul U., Deeks, Steven G., Schiffer, Joshua T., Lewin, Sharon R., Hellerstein, Marc K., McCune, Joseph M., Hunt, Peter W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846027/ https://www.ncbi.nlm.nih.gov/pubmed/33465157 http://dx.doi.org/10.1371/journal.ppat.1009214

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